Mostrando entradas con la etiqueta anorexia nerviosa. Mostrar todas las entradas
Mostrando entradas con la etiqueta anorexia nerviosa. Mostrar todas las entradas

miércoles, 3 de julio de 2013

NUTRICIÓN ANOREXIA NERVIOSA - OLIGOELEMENTOS.


1987 Sep;8(5):400-6

Zinc deficiency in anorexia nervosa.

Source

Department of Pediatrics, Stanford University Medical Center, Davis.

Abstract

Adolescents with anorexia nervosa were evaluated for clinical and biochemical evidence of zinc deficiency. To assess whether these patients would benefit from zinc supplementation, a double-blind, randomized, controlled trial was conducted. The mean zinc intake of the anorexic group calculated on the basis of three-day dietary records was 7.7 +/- 5.2 mg/day, which is significantly below the recommended daily allowance of 15 mg for adolescents (p less than 0.001). The mean urinary zinc excretion in the anorexic group was 257.1 +/- 212.7 micrograms/24 hours compared to 749.9 +/- 897.8 micrograms/24 hours in the control group (p less than 0.005). This result suggests that the zinc status of anorexia nervosa patients may be compromised due to an inadequate zinc intake. Zinc supplementation (50 mg elemental zinc/day) was followed by a decrease in the level of depression and anxiety as assessed by the Zung Depression Scale (p less than 0.05) and the State-Trait Anxiety Inventory (p less than 0.05), respectively. Our data suggest that individuals with anorexia nervosa may be at risk for zinc deficiency and may respond favorably after zinc supplementation.
PMID:
3312133
[PubMed - indexed for MEDLINE]
 

martes, 2 de julio de 2013

ANOREXIA NERVIOSA Y ZINC

How does zinc supplementation benefit anorexia nervosa?

Source

Eating Disorders Program, Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada. clbirm@interchange.ubc.ca

Abstract

BACKGROUND:

A randomized controlled trial of zinc supplementation in anorexia nervosa (AN) reported a two-fold increase of the rate of increase of body mass index (BMI) in the zinc group. Zinc is inexpensive, readily available and free of significant side effects. However, oral zinc supplementation is infrequently prescribed as an adjunctive treatment for AN. Understanding the mechanism of action of zinc may increase its use.

HYPOTHESIS:

Low zinc intake, which is very common in AN, adversely affects neurotransmitters in various parts of the brain, including gamma-amino butyric acid (GABA) and the amygdala, which are abnormal in AN. Zinc supplementation corrects these abnormalities, resulting in clinical benefit in AN.

CONCLUSIONS:

Oral administration of 14 mg of elemental zinc daily for 2 months in all patients with AN should be routine.
PMID:
17272939
[PubMed - indexed for MEDLINE]